PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_22981_iso_1

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

C2H2

Protein Properties

Length: 188aa MW: 21560.9 Da PI: 10.2663

Description

C2H2 family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_22981_iso_1	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	zf-C2H2	19	3.9e-06	79	101	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 ++C++C+k F r nL+ H r H cra_locus_22981_iso_1_len_649_ver_3 79 FVCEICNKGFQRDQNLQLHRRGH 101 89*******************88 PP
2	zf-C2H2	15.1	6.5e-05	155	177	1	23
EEETTTTEEESSHHHHHHHHHHT CS zf-C2H2 1 ykCpdCgksFsrksnLkrHirtH 23 +kC++C+k++ +s+ k H +t+ cra_locus_22981_iso_1_len_649_ver_3 155 WKCEKCSKRYAVQSDWKAHSKTC 177 58*****************9998 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:3.30.160.60	4.6E-6	78	101	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.51E-7	78	101	No hit	No description
Pfam	PF12171	2.2E-5	79	101	IPR022755	Zinc finger, double-stranded RNA binding
SMART	SM00355	0.017	79	101	IPR015880	Zinc finger, C2H2-like
PROSITE profile	PS50157	10.949	79	101	IPR007087	Zinc finger, C2H2
PROSITE pattern	PS00028	0	81	101	IPR007087	Zinc finger, C2H2
SMART	SM00355	260	120	150	IPR015880	Zinc finger, C2H2-like
Gene3D	G3DSA:3.30.160.60	1.2E-5	143	176	IPR013087	Zinc finger C2H2-type/integrase DNA-binding domain
SuperFamily	SSF57667	3.51E-7	150	175	No hit	No description
SMART	SM00355	130	155	175	IPR015880	Zinc finger, C2H2-like

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0003676	Molecular Function	nucleic acid binding
GO:0046872	Molecular Function	metal ion binding

Sequence ? help Back to Top
Protein Sequence Length: 188 aa Download sequence Send to blast
MAMMFPSLMS NSTSLSEDAN VSSITRVQDF CSLNPMLPTI SSNHLPQKIK KKRNLPGNPD 60 PNAEVIALSP KTLLATNRFV CEICNKGFQR DQNLQLHRRG HNLPWKLKQR NNKENKKRAY 120 VCPEPTCLHH HPSRALGDLT GIKKHYCRKH GEKKWKCEKC SKRYAVQSDW KAHSKTCGTR 180 EYRCDCGT

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5b3h_C	6e-20	151	188	3	40	Zinc finger protein JACKDAW
5b3h_F	6e-20	151	188	3	40	Zinc finger protein JACKDAW
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Functional Description ? help Back to Top
Source	Description
UniProt	Probable transcription factor. {ECO:0000305}.
UniProt	Transcription factor that regulates tissue boundaries and asymmetric cell division (PubMed:17785527, PubMed:25829440). Contributes to the sequestration of 'SHORT-ROOT' to the nucleus (PubMed:17785527, PubMed:25829440). Interacts with the SCR and MGP promoters (PubMed:21935722). Does not show transcription activity by itself, but regulates the transcription of downstream genes through interaction with other transcription factors (PubMed:21935722). Binds DNA via its zinc fingers (PubMed:24821766). Recognizes and binds to SCL3 promoter sequence 5'-AGACAA-3' to promotes its expression when in complex with RGA (PubMed:24821766). Positively involved in gibberellic acid (GA) signaling (PubMed:24821766). {ECO:0000269\|PubMed:17785527, ECO:0000269\|PubMed:21935722, ECO:0000269\|PubMed:24821766, ECO:0000269\|PubMed:25829440}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: Up-regulated by the transcription factor JKD, and down-regulated by SHR, SCR and itself. {ECO:0000269\|PubMed:21935722}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_021281006.1	1e-119	protein indeterminate-domain 12
Swissprot	O22759	2e-94	IDD12_ARATH; Protein indeterminate-domain 12
Swissprot	Q9ZWA6	2e-93	IDD3_ARATH; Zinc finger protein MAGPIE
TrEMBL	A0A061DRD1	1e-118	A0A061DRD1_THECC; Indeterminate(ID)-domain 12
STRING	EOX94636	1e-118	(Theobroma cacao)

Publications ? help Back to Top
Muñoz-Strale D,León G Identification of two highly specific pollen promoters using transcriptomic data. Plant Physiol. Biochem., 2014. 83: p. 292-9 [PMID:25208507] Moreno-Risueno MA, et al. Transcriptional control of tissue formation throughout root development. Science, 2015. 350(6259): p. 426-30 [PMID:26494755]