PlantTFDB - Plant Transcription Factor Database @ CBI, PKU

PlantRegMap/PlantTFDB v5.0

Plant Transcription Factor Database

Transcription Factor Information

Basic Information | Signature Domain | Sequence |

Basic Information? help Back to Top

TF ID

cra_locus_3799_iso_5

Organism

Catharanthus roseus

Taxonomic ID

4058

Taxonomic Lineage

cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus

Family

WRKY

Protein Properties

Length: 287aa MW: 32807.5 Da PI: 5.7846

Description

WRKY family protein

Gene Model

Gene Model ID	Type	Source	Coding Sequence
cra_locus_3799_iso_5	genome	MPGR	-

Signature Domain? help Back to Top

No.	Domain	Score	E-value	Start	End	HMM Start	HMM End
1	WRKY	91.6	6e-29	74	134	1	58
---SS-EEEEEEE--TT-SS-EEEEEE-ST...T---EEEEEE-SSSTTEEEEEEES--SS CS WRKY 1 ldDgynWrKYGqKevkgsefprsYYrCtsa...gCpvkkkversaedpkvveitYegeHnh 58 +dDgynWrKYGqK++ g+ fprsYYrCt++ gC ++k+v++s+ed +++e+tY+g+H + cra_locus_3799_iso_5_len_1190_ver_3 74 VDDGYNWRKYGQKDILGAIFPRSYYRCTHRytqGCLATKQVQKSEEDSSIFEVTYKGRHSC 134 59*************************99999***********************98 PP

Protein Features ? help Back to Top

Database	Entry ID	E-value	Start	End	InterPro ID	Description
Gene3D	G3DSA:2.20.25.80	6.3E-28	64	135	IPR003657	WRKY domain
PROSITE profile	PS50811	22.928	69	133	IPR003657	WRKY domain
SuperFamily	SSF118290	2.62E-25	72	134	IPR003657	WRKY domain
SMART	SM00774	1.2E-39	74	136	IPR003657	WRKY domain
Pfam	PF03106	5.0E-26	75	134	IPR003657	WRKY domain

Gene Ontology ? help Back to Top
GO Term	GO Category	GO Description
GO:0009751	Biological Process	response to salicylic acid
GO:0009816	Biological Process	defense response to bacterium, incompatible interaction
GO:0010150	Biological Process	leaf senescence
GO:0010193	Biological Process	response to ozone
GO:0010200	Biological Process	response to chitin
GO:0031347	Biological Process	regulation of defense response
GO:0042542	Biological Process	response to hydrogen peroxide
GO:0045893	Biological Process	positive regulation of transcription, DNA-templated
GO:0005634	Cellular Component	nucleus
GO:0009507	Cellular Component	chloroplast
GO:0003700	Molecular Function	transcription factor activity, sequence-specific DNA binding
GO:0043565	Molecular Function	sequence-specific DNA binding

Sequence ? help Back to Top
Protein Sequence Length: 287 aa Download sequence Send to blast
LAWNNNNNKS YKPSLKRKSF EFSSSHSSSP ITPITGYSSD RIVSKHDYSK KRKTLPKWRE 60 QVRVCSGIGQ EGPVDDGYNW RKYGQKDILG AIFPRSYYRC THRYTQGCLA TKQVQKSEED 120 SSIFEVTYKG RHSCVQTSNS TSKTASIQKE IFKPNKPLLV QENQDIQRLE DGLKVETKEL 180 KTREEIFPLF SFPYTQIEQE NVENQLLMSC YSPESESNFF ASPWEDMNNF IIGSILEKSS 240 VESDATTIAT PNSVTNDSSP FGDLEISIDD QVNFDPYIPL DTLAYFS

3D Structure ? help Back to Top

PDB ID	Evalue	Query Start	Query End	Hit Start	Hit End	Description
5w3x_B	3e-20	74	133	14	75	Disease resistance protein RRS1
5w3x_D	3e-20	74	133	14	75	Disease resistance protein RRS1
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Functional Description ? help Back to Top
Source	Description
UniProt	Transcription factor. Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:20409006). May regulate the early events of leaf senescence (PubMed:17369373, PubMed:20409006). Negatively regulates the expression of ESR/ESP (PubMed:20409006). Together with WRKY46 and WRKY70, promotes resistance to P.syringae, probably by enhancing salicylic acid (SA)- dependent genes. Contributes to the suppression of jasmonic acid (MeJA)-induced expression of PDF1.2 (PubMed:22325892). {ECO:0000269\|PubMed:17369373, ECO:0000269\|PubMed:20409006, ECO:0000269\|PubMed:22325892}.

Regulation -- Description ? help Back to Top
Source	Description
UniProt	INDUCTION: By salicylic acid (SA) (PubMed:22268143, PubMed:22325892). Strong accumulation during leaf senescence (PubMed:22268143). Down-regulated by jasmonate. Triggered by P.syringae (PubMed:22325892). {ECO:0000269\|PubMed:11449049, ECO:0000269\|PubMed:11506370, ECO:0000269\|PubMed:17369373, ECO:0000269\|PubMed:22268143, ECO:0000269\|PubMed:22325892}.

Annotation -- Protein ? help Back to Top
Source	Hit ID	E-value	Description
Refseq	XP_027162429.1	2e-81	probable WRKY transcription factor 53
Swissprot	Q9SUP6	4e-44	WRK53_ARATH; Probable WRKY transcription factor 53
TrEMBL	A0A068UKB5	3e-76	A0A068UKB5_COFCA; Uncharacterized protein
STRING	EOX95753	1e-68	(Theobroma cacao)

Publications ? help Back to Top
Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P An extracellular subtilase switch for immune priming in Arabidopsis. PLoS Pathog., 2013. 9(6): p. e1003445 [PMID:23818851] Ding Y, et al. Four distinct types of dehydration stress memory genes in Arabidopsis thaliana. BMC Plant Biol., 2013. 13: p. 229 [PMID:24377444] Singh V,Roy S,Singh D,Nandi AK Arabidopsis flowering locus D influences systemic-acquired-resistance- induced expression and histone modifications of WRKY genes. J. Biosci., 2014. 39(1): p. 119-26 [PMID:24499796] Zhang H, et al. Arabidopsis AtERF15 positively regulates immunity against Pseudomonas syringae pv. tomato DC3000 and Botrytis cinerea. Front Plant Sci, 2015. 6: p. 686 [PMID:26388886] Ramírez V,López A,Mauch-Mani B,Gil MJ,Vera P Correction: An Extracellular Subtilase Switch for Immune Priming in Arabidopsis. PLoS Pathog., 2016. 12(11): p. e1006003 [PMID:27806116] Chen X, et al. POWERDRESS interacts with HISTONE DEACETYLASE 9 to promote aging in Arabidopsis. Elife, 2017. [PMID:27873573] Nie P, et al. Induced Systemic Resistance against Botrytis cinerea by Bacillus cereus AR156 through a JA/ET- and NPR1-Dependent Signaling Pathway and Activates PAMP-Triggered Immunity in Arabidopsis. Front Plant Sci, 2017. 8: p. 238 [PMID:28293243] Ren Y,Li Y,Jiang Y,Wu B,Miao Y Phosphorylation of WHIRLY1 by CIPK14 Shifts Its Localization and Dual Functions in Arabidopsis. Mol Plant, 2017. 10(5): p. 749-763 [PMID:28412544] Sarkar S, et al. Interaction of Arabidopsis TGA3 and WRKY53 transcription factors on Cestrum yellow leaf curling virus (CmYLCV) promoter mediates salicylic acid-dependent gene expression in planta. Planta, 2018. 247(1): p. 181-199 [PMID:28913593] Crespo-Salvador Ó,Escamilla-Aguilar M,López-Cruz J,López-Rodas G,González-Bosch C Determination of histone epigenetic marks in Arabidopsis and tomato genes in the early response to Botrytis cinerea. Plant Cell Rep., 2018. 37(1): p. 153-166 [PMID:29119291] Yuan N, et al. STRESS INDUCED FACTOR 2, a Leucine-Rich Repeat Kinase Regulates Basal Plant Pathogen Defense. Plant Physiol., 2018. 176(4): p. 3062-3080 [PMID:29463771]