PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_6088_iso_3
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family WRKY
Protein Properties Length: 404aa    MW: 45593.2 Da    PI: 8.2268
Description WRKY family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_6088_iso_3genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRKY102.22.9e-3270126259
                                          --SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                                 WRKY   2 dDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                                          +DgynWrKYGqK+vkgse+prsYY+Ct+++Cp+kkkver+  +++++ei+Y+g+Hnh 
  cra_locus_6088_iso_3_len_2285_ver_3  70 EDGYNWRKYGQKQVKGSENPRSYYKCTFPSCPTKKKVERNL-EGHITEIVYKGNHNHA 126
                                          7****************************************.***************7 PP
2WRKY106.31.6e-33236294159
                                          ---SS-EEEEEEE--TT-SS-EEEEEE-STT---EEEEEE-SSSTTEEEEEEES--SS- CS
                                 WRKY   1 ldDgynWrKYGqKevkgsefprsYYrCtsagCpvkkkversaedpkvveitYegeHnhe 59 
                                          ldDgy+WrKYGqK+vkg+++prsYY+Ct+agCpv+k+ver+++d ++v++tYeg+Hnh+
  cra_locus_6088_iso_3_len_2285_ver_3 236 LDDGYRWRKYGQKVVKGNPNPRSYYKCTYAGCPVRKHVERASHDLRAVITTYEGKHNHD 294
                                          59********************************************************7 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
Gene3DG3DSA:2.20.25.804.0E-2758128IPR003657WRKY domain
SuperFamilySSF1182907.85E-2465128IPR003657WRKY domain
SMARTSM007742.1E-3369127IPR003657WRKY domain
PfamPF031065.1E-2470125IPR003657WRKY domain
PROSITE profilePS5081122.35570128IPR003657WRKY domain
Gene3DG3DSA:2.20.25.801.8E-37221296IPR003657WRKY domain
SuperFamilySSF1182901.31E-29228296IPR003657WRKY domain
PROSITE profilePS5081138.228231296IPR003657WRKY domain
SMARTSM007745.8E-39236295IPR003657WRKY domain
PfamPF031064.0E-26237294IPR003657WRKY domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0009409Biological Processresponse to cold
GO:0009414Biological Processresponse to water deprivation
GO:0009651Biological Processresponse to salt stress
GO:0009753Biological Processresponse to jasmonic acid
GO:0009788Biological Processnegative regulation of abscisic acid-activated signaling pathway
GO:0009938Biological Processnegative regulation of gibberellic acid mediated signaling pathway
GO:0010120Biological Processcamalexin biosynthetic process
GO:0010200Biological Processresponse to chitin
GO:0010508Biological Processpositive regulation of autophagy
GO:0042742Biological Processdefense response to bacterium
GO:0045893Biological Processpositive regulation of transcription, DNA-templated
GO:0050832Biological Processdefense response to fungus
GO:0070370Biological Processcellular heat acclimation
GO:0005634Cellular Componentnucleus
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0043565Molecular Functionsequence-specific DNA binding
GO:0044212Molecular Functiontranscription regulatory region DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 404 aa     Download sequence    Send to blast
MSQQNNKSTE SSSSTKTDIH HQSKSTPPNQ TNFSHGGNMQ TNTNDNNNNN NNNYSHQQPS  60
QYLREQRKSE DGYNWRKYGQ KQVKGSENPR SYYKCTFPSC PTKKKVERNL EGHITEIVYK  120
GNHNHAKPQS TRRSSSSSSI QNPQFLNSEF SNSQSNTFGE IDSFVNNENS SASFGDDDFE  180
QNSPVSNSRD DDDSEQPDAK RWKVDQNENE AISVSGSRTV REPRIVVQTT SDIDILDDGY  240
RWRKYGQKVV KGNPNPRSYY KCTYAGCPVR KHVERASHDL RAVITTYEGK HNHDVPAARG  300
SGSYTVNRPS AVNNSGGHLP MTTMASNNHN HNHSMNSSVP SFPNSLQNNN TLLRGQSHQT  360
PYTLQMLPNP GNFVPNSNMQ QMDNSFSLAK EEPKDDFFSD LSFC
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1wj2_A2e-3770297878Probable WRKY transcription factor 4
2lex_A2e-3770297878Probable WRKY transcription factor 4
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator (PubMed:26025535). Interacts specifically with the W box (5'-(T)TGAC[CT]-3'), a frequently occurring elicitor-responsive cis-acting element (PubMed:19199048, PubMed:26025535). Negative regulator of both gibberellic acid (GA) and abscisic acid (ABA) signaling in aleurone cells, probably by interfering with GAM1, via the specific repression of GA- and ABA-induced promoters (PubMed:15618416, PubMed:19199048, PubMed:26025535). {ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048, ECO:0000269|PubMed:26025535}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00299DAPTransfer from AT2G38470Download
Motif logo
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: Induced by abscisic acid (ABA) in aleurone cells, embryos, roots and leaves (PubMed:15618416, PubMed:19199048). Slightly down-regulated by gibberellic acid (GA) (PubMed:15618416). Accumulates in response to jasmonic acid (MeJA) (By similarity). {ECO:0000250|UniProtKB:Q6B6R4, ECO:0000269|PubMed:15618416, ECO:0000269|PubMed:19199048}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027068692.11e-164probable WRKY transcription factor 33
SwissprotQ6IEQ71e-118WRK24_ORYSJ; WRKY transcription factor WRKY24
TrEMBLA0A068VGV01e-164A0A068VGV0_COFCA; Uncharacterized protein
STRINGXP_009615564.11e-144(Nicotiana tomentosiformis)
Publications ? help Back to Top
  1. Kikuchi S, et al.
    Collection, mapping, and annotation of over 28,000 cDNA clones from japonica rice.
    Science, 2003. 301(5631): p. 376-9
    [PMID:12869764]
  2. Zhang ZL, et al.
    A negative regulator encoded by a rice WRKY gene represses both abscisic acid and gibberellins signaling in aleurone cells.
    Plant Mol. Biol., 2009. 70(1-2): p. 139-51
    [PMID:19199048]
  3. Basu S,Roychoudhury A
    Expression profiling of abiotic stress-inducible genes in response to multiple stresses in rice (Oryza sativa L.) varieties with contrasting level of stress tolerance.
    Biomed Res Int, 2014. 2014: p. 706890
    [PMID:25110688]
  4. Zhang L, et al.
    Three WRKY transcription factors additively repress abscisic acid and gibberellin signaling in aleurone cells.
    Plant Sci., 2015. 236: p. 214-22
    [PMID:26025535]