PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_8562_iso_2
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family AP2
Protein Properties Length: 630aa    MW: 70447.9 Da    PI: 7.8071
Description AP2 family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_8562_iso_2genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1AP2513.5e-16255314155
                                  AP2   1 sgykGVrwdkkrgrWvAeIrd.pse.ng..kr.krfslgkfgtaeeAakaaiaarkkleg 55 
                                          s+y+GV++++++gr++A+++d  ++  g  ++ ++++lg ++ +e+Aa+a++ a++k++g
  cra_locus_8562_iso_2_len_2136_ver_3 255 SQYRGVTRHRWTGRYEAHLWDnSCKkEGqsRKgRQVYLGGYDMEEKAARAYDLAALKYWG 314
                                          78*******************988886678446*************************98 PP
2AP222.33.2e-07359393341
                                  AP2   3 ykGVrwdkkrgrWvAeIrdpsengkrkrfslgkfgtaee 41 
                                          y+GV+++++ grW A+I  +     +k  +lg+f   + 
  cra_locus_8562_iso_2_len_2136_ver_3 359 YRGVTRHHQHGRWQARIGRVAG---NKDLYLGTFSE-FN 393
                                          9***************988532...5********77.55 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SuperFamilySSF541711.05E-16255324IPR016177DNA-binding domain
PfamPF008476.1E-13255314IPR001471AP2/ERF domain
CDDcd000186.08E-22255322No hitNo description
PROSITE profilePS5103219.203256322IPR001471AP2/ERF domain
SMARTSM003803.1E-29256328IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.104.2E-16256323IPR001471AP2/ERF domain
PRINTSPR003676.8E-5257268IPR001471AP2/ERF domain
PRINTSPR003676.8E-5304324IPR001471AP2/ERF domain
SuperFamilySSF541711.11E-5357392IPR016177DNA-binding domain
CDDcd000187.93E-13357443No hitNo description
PROSITE profilePS510329.137358416IPR001471AP2/ERF domain
SMARTSM003803.6E-10358447IPR001471AP2/ERF domain
Gene3DG3DSA:3.30.730.101.8E-4358391IPR001471AP2/ERF domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0003677Molecular FunctionDNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 630 aa     Download sequence    Send to blast
XAALSCPPPP FNYPAMYYGM EGENAAAYCS PLTVMPLKSD GSLCLMEAIN RSQPPQGMVT  60
STPKLENFFG GTTMGTHHYE ASDRGGVMAL SLDNSSMYYH GNSNIQDFLN NPQGNSRQIQ  120
HQDYSSFRET QLSEETNNLH HQLPTTISDN DISNMKTTWV SRDYTVDHSL DQKMNGCIGD  180
NVGYGDLQSL TLSMSPGSQS SCITGGSHQI SPAVTTECTA AAIETKKRGP EKADQQQPKQ  240
IIHRKSIDTF GQRTSQYRGV TRHRWTGRYE AHLWDNSCKK EGQSRKGRQV YLGGYDMEEK  300
AARAYDLAAL KYWGPSTHIN FPLENYQQQL EEMKNMSRQE YVAHLRRKSS GFSRGASMYR  360
GVTRHHQHGR WQARIGRVAG NKDLYLGTFS EFNANLDKMN FLRITEFAXE NFINRYTRGS  420
CRGNDIAAIK FRGVNAVTNF DISRYDVDRI MASNTLLAGD LARRNKNPES SNSPNYLQGN  480
EENNVSKETT NDNNNNNVVL DWNMALHQQQ QHHFSQPCPK PPPHHPPVGG GVLEDFKTSS  540
FSMPLNEMIG IEQAKMMTHF SDSSSSLVTS LSCSREGSPD KNCVPIHLAM PPSAAASKLF  600
ISPSQTVNSW IPSTQIRPHL PVFAAWTDTT
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that recognizes and binds to the DNA consensus sequence 5'-CAC[AG]N[AT]TNCCNANG-3'. Required for the initiation and growth of ovules integumenta, and for the development of female gametophyte. Plays a critical role in the development of gynoecium marginal tissues (e.g. stigma, style and septa), and in the fusion of carpels and of medial ridges leading to ovule primordia. Also involved in organs initiation and development, including floral organs. Maintains the meristematic competence of cells and consequently sustains expression of cell cycle regulators during organogenesis, thus controlling the final size of each organ by controlling their cell number. Regulates INO autoinduction and expression pattern. As ANT promotes petal cell identity and mediates down-regulation of AG in flower whorl 2, it functions as a class A homeotic gene. {ECO:0000269|PubMed:10528263, ECO:0000269|PubMed:10639184, ECO:0000269|PubMed:10948255, ECO:0000269|PubMed:11041883, ECO:0000269|PubMed:12183381, ECO:0000269|PubMed:12271029, ECO:0000269|PubMed:12655002, ECO:0000269|PubMed:8742706, ECO:0000269|PubMed:8742707, ECO:0000269|PubMed:9001406, ECO:0000269|PubMed:9093862, ECO:0000269|PubMed:9118807}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_027178540.10.0AP2-like ethylene-responsive transcription factor ANT isoform X2
SwissprotQ389141e-151ANT_ARATH; AP2-like ethylene-responsive transcription factor ANT
TrEMBLA0A1J6J6A40.0A0A1J6J6A4_NICAT; Ap2-like ethylene-responsive transcription factor ant
STRINGXP_009589482.10.0(Nicotiana tomentosiformis)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA20742460
Publications ? help Back to Top
  1. Heyndrickx KS,Vandepoele K
    Systematic identification of functional plant modules through the integration of complementary data sources.
    Plant Physiol., 2012. 159(3): p. 884-901
    [PMID:22589469]
  2. Horstman A,Willemsen V,Boutilier K,Heidstra R
    AINTEGUMENTA-LIKE proteins: hubs in a plethora of networks.
    Trends Plant Sci., 2014. 19(3): p. 146-57
    [PMID:24280109]
  3. Li C, et al.
    Ectopic expression of a maize hybrid down-regulated gene ZmARF25 decreases organ size by affecting cellular proliferation in Arabidopsis.
    PLoS ONE, 2014. 9(4): p. e94830
    [PMID:24756087]
  4. Wynn AN,Seaman AA,Jones AL,Franks RG
    Novel functional roles for PERIANTHIA and SEUSS during floral organ identity specification, floral meristem termination, and gynoecial development.
    Front Plant Sci, 2014. 5: p. 130
    [PMID:24778638]
  5. Randall RS, et al.
    AINTEGUMENTA and the D-type cyclin CYCD3;1 regulate root secondary growth and respond to cytokinins.
    Biol Open, 2015. 4(10): p. 1229-36
    [PMID:26340943]
  6. Meng LS,Wang ZB,Yao SQ,Liu A
    The ARF2-ANT-COR15A gene cascade regulates ABA-signaling-mediated resistance of large seeds to drought in Arabidopsis.
    J. Cell. Sci., 2015. 128(21): p. 3922-32
    [PMID:26395398]
  7. Yamaguchi N,Jeong CW,Nole-Wilson S,Krizek BA,Wagner D
    AINTEGUMENTA and AINTEGUMENTA-LIKE6/PLETHORA3 Induce LEAFY Expression in Response to Auxin to Promote the Onset of Flower Formation in Arabidopsis.
    Plant Physiol., 2016. 170(1): p. 283-93
    [PMID:26537561]
  8. Krizek BA, et al.
    RNA-Seq Links the Transcription Factors AINTEGUMENTA and AINTEGUMENTA-LIKE6 to Cell Wall Remodeling and Plant Defense Pathways.
    Plant Physiol., 2016. 171(3): p. 2069-84
    [PMID:27208279]
  9. Han H,Krizek BA
    AINTEGUMENTA-LIKE6 can functionally replace AINTEGUMENTA but alters Arabidopsis flower development when misexpressed at high levels.
    Plant Mol. Biol., 2016. 92(4-5): p. 597-612
    [PMID:27605095]
  10. Karpinska B,Alomrani SO,Foyer CH
    Inhibitor-induced oxidation of the nucleus and cytosol in Arabidopsis thaliana: implications for organelle to nucleus retrograde signalling.
    Philos. Trans. R. Soc. Lond., B, Biol. Sci., 2018.
    [PMID:28808105]
  11. Li B, et al.
    Network-Guided Discovery of Extensive Epistasis between Transcription Factors Involved in Aliphatic Glucosinolate Biosynthesis.
    Plant Cell, 2018. 30(1): p. 178-195
    [PMID:29317470]