PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID cra_locus_8867_iso_3
Organism
Catharanthus roseus
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Catharanthinae; Catharanthus
Family E2F/DP
Protein Properties Length: 396aa    MW: 43266.6 Da    PI: 9.1354
Description E2F/DP family protein
Gene Model
Gene Model ID Type Source Coding Sequence
cra_locus_8867_iso_3genomeMPGR-
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1E2F_TDP56.35.2e-18103185271
                              E2F_TDP   2 keksLrlltqkflklleksee.givtlnevakeLvse................dvknkrRRiYDilNVLealnl 58 
                                          ++++Lr++++k   ++ek+e+ g++t+neva+eLv+e                d+k+      D+lNVL+a+++
  cra_locus_8867_iso_3_len_1548_ver_3 103 TGRGLRQFSMK---VCEKVESkGRTTYNEVADELVAEfadpnngvstpdqqqyDEKKYTSTSDDALNVLMAMDI 173
                                          689********...*****999**************************999887777777788*********** PP

                              E2F_TDP  59 iekkekneirwkg 71 
                                          i+k +k+ei+wkg
  cra_locus_8867_iso_3_len_1548_ver_3 174 ISK-DKKEIQWKG 185
                                          ***.*******98 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PIRSFPIRSF0094041.3E-1186396IPR015648Transcription factor DP
Gene3DG3DSA:1.10.10.101.8E-3798190IPR011991Winged helix-turn-helix DNA-binding domain
SMARTSM013729.0E-20102185IPR003316E2F/DP family, winged-helix DNA-binding domain
SuperFamilySSF467859.93E-13105186IPR011991Winged helix-turn-helix DNA-binding domain
PfamPF023198.7E-16105185IPR003316E2F/DP family, winged-helix DNA-binding domain
CDDcd144585.57E-36190332IPR014889Transcription factor DP, C-terminal
SMARTSM011386.6E-58192394IPR014889Transcription factor DP, C-terminal
SuperFamilySSF1440743.4E-31259341No hitNo description
PfamPF087813.5E-31260364IPR014889Transcription factor DP, C-terminal
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0042023Biological ProcessDNA endoreduplication
GO:0005634Cellular Componentnucleus
GO:0005667Cellular Componenttranscription factor complex
GO:0005737Cellular Componentcytoplasm
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
GO:0046982Molecular Functionprotein heterodimerization activity
Sequence ? help Back to Top
Protein Sequence    Length: 396 aa     Download sequence    Send to blast
MVKNKEDGLK NPSTTSRGGN GGGGGAGATR SWGTTVSGQS VSTSGSVGSP SSRSEAAIAT  60
PASESTFMRL NNLDIQGDDA GSQGAAGNRK KKRGQRAVGG DKTGRGLRQF SMKVCEKVES  120
KGRTTYNEVA DELVAEFADP NNGVSTPDQQ QYDEKKYTST SDDALNVLMA MDIISKDKKE  180
IQWKGLPRTS LNDIEELKNE RLGLRNRIEK KAAYLEELEE QVRKIRLDAK SFFSFSGVML  240
LLLQFYKFLF LGFSHFSFKK YVGLQNLIQR NEQLYGSGNA PSGGVALPFI LVQTRPHATV  300
EVEISEDMQL VHFDFNSTPF ELHDDNYVLK AMKFSEKPES ESGAQKVPTD GGESSSMPNV  360
FQPQAPPAPS RSNIPVRPPT SPPLPGILKA RVKHEH
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
1cf7_B8e-3296190193PROTEIN (TRANSCRIPTION FACTOR DP-2)
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtInvolved in the regulation of the G1/S transition. Increases the DNA binding activity of E2F proteins after heterodimerization. The complex DPB/E2FC restricts cell division and lateral root initiation and may function as a negative regulator of E2F-regulated genes. The interaction with SKP2A is controlled by auxin. {ECO:0000269|PubMed:11891240, ECO:0000269|PubMed:16920782}.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_011075421.10.0transcription factor-like protein DPB isoform X1
RefseqXP_027068073.10.0transcription factor-like protein DPB isoform X1
SwissprotQ9FNY21e-155DPB_ARATH; Transcription factor-like protein DPB
TrEMBLA0A2G9FZK60.0A0A2G9FZK6_9LAMI; E2F-like protein
STRINGXP_010241817.10.0(Nelumbo nucifera)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
AsteridsOGEA62652435