PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID evm.model.supercontig_129.72
Organism
Carica papaya
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Embryophyta; Tracheophyta; Euphyllophyta; Spermatophyta; Magnoliophyta; Mesangiospermae; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Caricaceae; Carica
Family GRF
Protein Properties Length: 611aa    MW: 65013.2 Da    PI: 7.7065
Description GRF family protein
Gene Model
Gene Model ID Type Source Coding Sequence
evm.model.supercontig_129.72genomeASGPBView CDS
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1WRC76.62.6e-24226270145
                           WRC   1 daepgrCrRtDGKkWRCsrrvlegkklCErHlhrgrsrsrkskee 45 
                                   d+epgrCrRtDGKkWRCsr++++++k+CErH++rgr+rsrk++e 
  evm.model.supercontig_129.72 226 DPEPGRCRRTDGKKWRCSRDAVADQKYCERHINRGRHRSRKPVEG 270
                                   79****************************************985 PP
2QLQ55.71.5e-19156192137
                           QLQ   1 saFTaaQlqlLksQilAyKyLaanqPvPpeLlqaiqk 37 
                                   ++F+++Q+ +L++Q+l+yKy+ an+PvP++Ll+ ++k
  evm.model.supercontig_129.72 156 GPFSPSQWIELEHQALIYKYITANVPVPSNLLMSLKK 192
                                   59******************************99875 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
SMARTSM009514.1E-11156192IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166621.918157192IPR014978Glutamine-Leucine-Glutamine, QLQ
PfamPF088801.7E-13157190IPR014978Glutamine-Leucine-Glutamine, QLQ
PROSITE profilePS5166725.287226270IPR014977WRC domain
PfamPF088797.9E-21227269IPR014977WRC domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0006355Biological Processregulation of transcription, DNA-templated
GO:0009624Biological Processresponse to nematode
GO:0048364Biological Processroot development
GO:0048366Biological Processleaf development
GO:0061062Biological Processregulation of nematode larval development
GO:0005634Cellular Componentnucleus
GO:0005524Molecular FunctionATP binding
Sequence ? help Back to Top
Protein Sequence    Length: 611 aa     Download sequence    Send to blast
MDFGVLGLEG LVGPESAGAS SQPPPAPDTN HNVLGSGFVR QERSRPGEDD WRTSKVAKTM  60
PLHQATTSPL LRSNTNSAVA ADTSSQQGHM LSFSSAQSEV PFLTRDCGML LQRSSQNTPP  120
YHQPTAATAS GYARNAGYVS GSLNATMHGH FAGGRGPFSP SQWIELEHQA LIYKYITANV  180
PVPSNLLMSL KKSLYPFSLT GSSAGSLSSN SLGWGSFHLG FSGSTDPEPG RCRRTDGKKW  240
RCSRDAVADQ KYCERHINRG RHRSRKPVEG QIGHAATGPA ANSKLAVVPP MTSSMSSTSA  300
IVPSSGAPNS LAISQHQLKN LKPVVANRPN PSADSLINRV QDPCDLSTLS SAINGKSNNT  360
AFSIQKQDIL LEESSHSEFG LVSSDSLLNP SQRSGYMSSK NYVSYLDFGD QETQEQHPFH  420
QFMDDWPKDQ SNHSVITWHE ELKSDWTQLS MSIPMPSSEF SSSTSSPTQE KLALSPLRLS  480
RELDPAIQMG LRLNSNIGEL SKKRNNMVPP ISWGSSMGGP LGEVLTSTSN SLATIKNSSA  540
ALNLISEGWD GSPQLGSSPT GVLQKSAFGS LSNSSSGSSS IAENKKGNEG ASLCDDVLGS  600
SLASSSIPSM *
Functional Description ? help Back to Top
Source Description
UniProtTranscription activator that plays a role in the regulation of cell expansion in leaf and cotyledons tissues. Component of a network formed by miR396, the GRFs and their interacting factors (GIFs) acting in the regulation of meristem function, at least partially through the control of cell proliferation. microRNA396-GRF1/GRF3 regulatory module acts as a developmental regulator in the reprogramming of root cells during cyst nematode infection, leading to the formation of the syncytium. {ECO:0000269|PubMed:12974814, ECO:0000269|PubMed:15326298, ECO:0000269|PubMed:22419826, ECO:0000269|PubMed:22751317}.
Cis-element ? help Back to Top
SourceLink
PlantRegMapevm.model.supercontig_129.72
Regulation -- Description ? help Back to Top
Source Description
UniProtINDUCTION: microRNA 396 (miR396a or miR396b) negatively regulates growth-regulating factors (GRF1-4 and GRF7-9). Up-regulated in response to cyst nematode infection. {ECO:0000269|PubMed:15200956, ECO:0000269|PubMed:19453503, ECO:0000269|PubMed:20023165, ECO:0000269|PubMed:22419826}.
Regulation -- PlantRegMap ? help Back to Top
Source Upstream Regulator Target Gene
PlantRegMapRetrieve-
Annotation -- Nucleotide ? help Back to Top
Source Hit ID E-value Description
GenBankAM4886162e-52AM488616.1 Vitis vinifera contig VV78X030262.6, whole genome shotgun sequence.
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_021890517.10.0growth-regulating factor 1
SwissprotO810011e-128GRF1_ARATH; Growth-regulating factor 1
TrEMBLA0A1R3GEB10.0A0A1R3GEB1_COCAP; Growth-regulating factor 8
STRINGevm.model.supercontig_129.720.0(Carica papaya)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
MalvidsOGEM14542886
Representative plantOGRP33571226
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G22840.11e-108growth-regulating factor 1
Publications ? help Back to Top
  1. Casadevall R,Rodriguez RE,Debernardi JM,Palatnik JF,Casati P
    Repression of growth regulating factors by the microRNA396 inhibits cell proliferation by UV-B radiation in Arabidopsis leaves.
    Plant Cell, 2013. 25(9): p. 3570-83
    [PMID:24076976]
  2. Liu J,Rice JH,Chen N,Baum TJ,Hewezi T
    Synchronization of developmental processes and defense signaling by growth regulating transcription factors.
    PLoS ONE, 2014. 9(5): p. e98477
    [PMID:24875638]
  3. Cao Y,Han Y,Jin Q,Lin Y,Cai Y
    Comparative Genomic Analysis of the GRF Genes in Chinese Pear (Pyrus bretschneideri Rehd), Poplar (Populous), Grape (Vitis vinifera), Arabidopsis and Rice (Oryza sativa).
    Front Plant Sci, 2016. 7: p. 1750
    [PMID:27933074]