PlantTFDB
PlantRegMap/PlantTFDB v5.0
Plant Transcription Factor Database
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(e.g., LFY)
Transcription Factor Information
Basic Information | Signature Domain | Sequence | 
Basic Information? help Back to Top
TF ID kfl00801_0040
Organism
Klebsormidium flaccidum
Taxonomic ID
Taxonomic Lineage
cellular organisms; Eukaryota; Viridiplantae; Streptophyta; Klebsormidiophyceae; Klebsormidiales; Klebsormidiaceae; Klebsormidium
Family EIL
Protein Properties Length: 718aa    MW: 77803.9 Da    PI: 6.3002
Description EIL family protein
Gene Model
Gene Model ID Type Source Coding Sequence
kfl00801_0040genomeKFGPView Nucleic Acid
Signature Domain? help Back to Top
Signature Domain
No. Domain Score E-value Start End HMM Start HMM End
1EIN3394.41.5e-120604352353
                    XXXXXXXXXXXXXXXXXXXXXX..XXXXX.XXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX CS
           EIN3   2 elkkrmwkdqmllkrlkerkkqlledkeaatgakksnksneqarrkkmsraQDgiLkYMlkemevcnaqGfvYgiipekgkpvegasdsLraWWke 97 
                     l++rmw+d  +l+rlker ++    ke a ++ ++++s+eqarrk+msra D iLkYMlk+mev++aqGfvYgiipekgkpv gas++LraWWk+
  kfl00801_0040  60 GLERRMWRDMWKLRRLKERLRR----KEGADEKPQQKQSQEQARRKQMSRAHDEILKYMLKMMEVYKAQGFVYGIIPEKGKPVGGASENLRAWWKD 151
                    589***************9997....66667789999*********************************************************** PP

                    XXXXXXXXXXXXXXXXXXXXXXXXXXXX....XX----STTS-HHHHHHHHHHHSSSSSS-TTS--TTT--HHHH---S--HHHHHHT--TT--.- CS
           EIN3  98 kvefdrngpaaiskyqaknlilsgesslqtersseshslselqDTtlgSLLsalmqhcdppqrrfplekgvepPWWPtGkelwwgelglskdqgtp 193
                    kv+fdrngpaa +ky+a+++ + g+ + q+ +  +++sl elqDTtlgSLLsalmqhc+ppqrr+plek v+pPWWPtG+e+ww+++gl+   g+p
  kfl00801_0040 152 KVRFDRNGPAAAAKYAAEHASQWGGPNPQSPPAPTPSSLAELQDTTLGSLLSALMQHCTPPQRRYPLEKEVAPPWWPTGEEEWWPQVGLPPGSGPP 247
                    *****************999999999999*9***************************************************************** PP

                    ----GGG--HHHHHHHHHHHHHHTGGGHHHHHHTTTTSSSSTTT--SHHHHHHHHHHTTTTT-S--XXXXXXXXXXXXXXXXXXXX...XXXXXX. CS
           EIN3 194 pykkphdlkkawkvsvLtavikhmsptieeirelerqskylqdkmsakesfallsvlnqeekecatvsahssslrkqspkvtlsce...qkedve. 285
                    py+kph+lkkawkv+vLtavikhm+p+i+++r+l+ qsk lqdkm+a+es+++l+vl qe ++      h        p++ +s e   +++dve 
  kfl00801_0040 248 PYRKPHNLKKAWKVGVLTAVIKHMAPDISKVRKLVQQSKGLQDKMTARESATWLAVLAQEGAQNGGGGHH-----GPGPAMMVSGEgsaEDYDVEg 338
                    ************************************************************8755433333.....345555555431114555555 PP

                    ..............XXXXXX.XXXXXXXXXX...............................XXXXXXXXXXXXXXXXXXXXX......XXXXXXX CS
           EIN3 286 ..............gkkeskikhvqavktta...............................gfpvvrkrkkkpsesakvsskevsrtcqssqfrg 336
                                  g               +                               + p+  ++++ p+e+     +    tcq   +++
  kfl00801_0040 339 pakpspplvitslpG---------------EdegekasprtglgvldhgnrgvansssvsiaSPPLGPRKRASPGEQPHSGGT-LLFTCQYIMCPR 418
                    443333333222221...............13444555566777888888999999999998888888888777777776655.78********** PP

                    .XXXXXXXXXXXXXXXX CS
           EIN3 337 setelifadknsisqne 353
                    +e  + f+++ +++ ++
  kfl00801_0040 419 HEAWNAFPNRAARNAHQ 435
                    **************998 PP
Protein Features ? help Back to Top
3D Structure
Database Entry ID E-value Start End InterPro ID Description
PfamPF048735.9E-11460307No hitNo description
Gene3DG3DSA:1.10.3180.105.8E-66184309IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
SuperFamilySSF1167683.92E-57188308IPR023278Ethylene insensitive 3-like protein, DNA-binding domain
Gene Ontology ? help Back to Top
GO Term GO Category GO Description
GO:0001666Biological Processresponse to hypoxia
GO:0009873Biological Processethylene-activated signaling pathway
GO:0042742Biological Processdefense response to bacterium
GO:0071281Biological Processcellular response to iron ion
GO:0005634Cellular Componentnucleus
GO:0000976Molecular Functiontranscription regulatory region sequence-specific DNA binding
GO:0003700Molecular Functiontranscription factor activity, sequence-specific DNA binding
Sequence ? help Back to Top
Protein Sequence    Length: 718 aa     Download sequence    Send to blast
MAQGQDVKRR ASTLEGEWLK SLAANVGEQC GEQSTVDIAD MLDASLQDDE VSDDEVDVEG  60
LERRMWRDMW KLRRLKERLR RKEGADEKPQ QKQSQEQARR KQMSRAHDEI LKYMLKMMEV  120
YKAQGFVYGI IPEKGKPVGG ASENLRAWWK DKVRFDRNGP AAAAKYAAEH ASQWGGPNPQ  180
SPPAPTPSSL AELQDTTLGS LLSALMQHCT PPQRRYPLEK EVAPPWWPTG EEEWWPQVGL  240
PPGSGPPPYR KPHNLKKAWK VGVLTAVIKH MAPDISKVRK LVQQSKGLQD KMTARESATW  300
LAVLAQEGAQ NGGGGHHGPG PAMMVSGEGS AEDYDVEGPA KPSPPLVITS LPGEDEGEKA  360
SPRTGLGVLD HGNRGVANSS SVSIASPPLG PRKRASPGEQ PHSGGTLLFT CQYIMCPRHE  420
AWNAFPNRAA RNAHQASCAF KVEEGGVGGG REAPRNENGG LMKSELRQWE ARLGGEAHGE  480
AGPHAPPHDI FKSPDLLPLH YPNDIFAGLF SEGGEHVVEK GGGQFGNPLD SFSLDALDGL  540
DGQHWGGEAA VQFPRPVTPL EEVGIDGAFH THLPGGQHAP HHHPPVLMGI DHSEQRQRAA  600
QSHTPQGFGS FQGFSGGALE NSLPPTNVQH DSLSMYTTSG LLEQIPQTAA QQGHEQRSTD  660
WLGLQQAEML FGSGVPFALE PPKRPSRQAS VAGSLVGDQS KSPESAAVSE MGDSEFVW
3D Structure ? help Back to Top
Structure
PDB ID Evalue Query Start Query End Hit Start Hit End Description
4zds_A3e-621863072123Protein ETHYLENE INSENSITIVE 3
4zds_B3e-621863072123Protein ETHYLENE INSENSITIVE 3
Search in ModeBase
Functional Description ? help Back to Top
Source Description
UniProtProbable transcription factor acting as a positive regulator in the ethylene response pathway. Is required for ethylene responsiveness in adult plant tissues. Binds a primary ethylene response element present in the ETHYLENE-RESPONSE-FACTOR1 promoter with consequence to activate the transcription of this gene. {ECO:0000269|PubMed:9215635, ECO:0000269|PubMed:9851977}.
Binding Motif ? help Back to Top
Motif ID Method Source Motif file
MP00367DAPTransfer from AT3G20770Download
Motif logo
Annotation -- Protein ? help Back to Top
Source Hit ID E-value Description
RefseqXP_002276380.11e-143PREDICTED: ETHYLENE INSENSITIVE 3-like 1 protein
RefseqXP_004140927.11e-143PREDICTED: ETHYLENE INSENSITIVE 3-like 1 protein
RefseqXP_010659025.11e-143PREDICTED: ETHYLENE INSENSITIVE 3-like 1 protein
RefseqXP_011656591.11e-143PREDICTED: ETHYLENE INSENSITIVE 3-like 1 protein
SwissprotO246061e-132EIN3_ARATH; Protein ETHYLENE INSENSITIVE 3
TrEMBLA0A1Y1IPV60.0A0A1Y1IPV6_KLENI; ETHYLENE-INSENSITIVE3-like protein
STRINGVIT_13s0047g00250.t011e-142(Vitis vinifera)
STRINGXP_004140927.11e-142(Cucumis sativus)
STRINGXP_004172838.11e-143(Cucumis sativus)
Orthologous Group ? help Back to Top
LineageOrthologous Group IDTaxa NumberGene Number
Representative plantOGRP5631682
Best hit in Arabidopsis thaliana ? help Back to Top
Hit ID E-value Description
AT2G27050.13e-85ETHYLENE-INSENSITIVE3-like 1
Publications ? help Back to Top
  1. Duarte JM, et al.
    Expression pattern shifts following duplication indicative of subfunctionalization and neofunctionalization in regulatory genes of Arabidopsis.
    Mol. Biol. Evol., 2006. 23(2): p. 469-78
    [PMID:16280546]
  2. Kim HG, et al.
    GDSL LIPASE1 modulates plant immunity through feedback regulation of ethylene signaling.
    Plant Physiol., 2013. 163(4): p. 1776-91
    [PMID:24170202]
  3. Zhong S, et al.
    Ethylene-orchestrated circuitry coordinates a seedling's response to soil cover and etiolated growth.
    Proc. Natl. Acad. Sci. U.S.A., 2014. 111(11): p. 3913-20
    [PMID:24599595]
  4. Kim HG, et al.
    GDSL lipase 1 regulates ethylene signaling and ethylene-associated systemic immunity in Arabidopsis.
    FEBS Lett., 2014. 588(9): p. 1652-8
    [PMID:24631536]
  5. Jourda C, et al.
    Expansion of banana (Musa acuminata) gene families involved in ethylene biosynthesis and signalling after lineage-specific whole-genome duplications.
    New Phytol., 2014. 202(3): p. 986-1000
    [PMID:24716518]
  6. Zhang GB,Yi HY,Gong JM
    The Arabidopsis ethylene/jasmonic acid-NRT signaling module coordinates nitrate reallocation and the trade-off between growth and environmental adaptation.
    Plant Cell, 2014. 26(10): p. 3984-98
    [PMID:25326291]
  7. Wang J, et al.
    Arabidopsis ROOT HAIR DEFECTIVE3 is involved in nitrogen starvation-induced anthocyanin accumulation.
    J Integr Plant Biol, 2015. 57(8): p. 708-21
    [PMID:25494721]
  8. Ge XM, et al.
    Heterotrimeric G protein mediates ethylene-induced stomatal closure via hydrogen peroxide synthesis in Arabidopsis.
    Plant J., 2015. 82(1): p. 138-50
    [PMID:25704455]
  9. Kazan K
    Diverse roles of jasmonates and ethylene in abiotic stress tolerance.
    Trends Plant Sci., 2015. 20(4): p. 219-29
    [PMID:25731753]
  10. Yang C, et al.
    MAOHUZI6/ETHYLENE INSENSITIVE3-LIKE1 and ETHYLENE INSENSITIVE3-LIKE2 Regulate Ethylene Response of Roots and Coleoptiles and Negatively Affect Salt Tolerance in Rice.
    Plant Physiol., 2015. 169(1): p. 148-65
    [PMID:25995326]
  11. Contreras-Cornejo HA, et al.
    Mitogen-Activated Protein Kinase 6 and Ethylene and Auxin Signaling Pathways Are Involved in Arabidopsis Root-System Architecture Alterations by Trichoderma atroviride.
    Mol. Plant Microbe Interact., 2015. 28(6): p. 701-10
    [PMID:26067203]
  12. Li J,Xu HH,Liu WC,Zhang XW,Lu YT
    Ethylene Inhibits Root Elongation during Alkaline Stress through AUXIN1 and Associated Changes in Auxin Accumulation.
    Plant Physiol., 2015. 168(4): p. 1777-91
    [PMID:26109425]
  13. Street IH, et al.
    Ethylene Inhibits Cell Proliferation of the Arabidopsis Root Meristem.
    Plant Physiol., 2015. 169(1): p. 338-50
    [PMID:26149574]
  14. Ju C,Chang C
    Mechanistic Insights in Ethylene Perception and Signal Transduction.
    Plant Physiol., 2015. 169(1): p. 85-95
    [PMID:26246449]
  15. Qing D, et al.
    Quantitative and Functional Phosphoproteomic Analysis Reveals that Ethylene Regulates Water Transport via the C-Terminal Phosphorylation of Aquaporin PIP2;1 in Arabidopsis.
    Mol Plant, 2016. 9(1): p. 158-174
    [PMID:26476206]
  16. Zhang Y,Liu J,Chai J,Xing D
    Mitogen-activated protein kinase 6 mediates nuclear translocation of ORE3 to promote ORE9 gene expression in methyl jasmonate-induced leaf senescence.
    J. Exp. Bot., 2016. 67(1): p. 83-94
    [PMID:26507893]
  17. Li X,Pan Y,Chang B,Wang Y,Tang Z
    NO Promotes Seed Germination and Seedling Growth Under High Salt May Depend on EIN3 Protein in Arabidopsis.
    Front Plant Sci, 2015. 6: p. 1203
    [PMID:26779234]
  18. Yu Y, et al.
    Salt Stress and Ethylene Antagonistically Regulate Nucleocytoplasmic Partitioning of COP1 to Control Seed Germination.
    Plant Physiol., 2016. 170(4): p. 2340-50
    [PMID:26850275]
  19. Pelagio-Flores R,Ruiz-Herrera LF,López-Bucio J
    Serotonin modulates Arabidopsis root growth via changes in reactive oxygen species and jasmonic acid-ethylene signaling.
    Physiol Plant, 2016. 158(1): p. 92-105
    [PMID:26864878]
  20. Tao S, et al.
    The THO/TREX Complex Active in miRNA Biogenesis Negatively Regulates Root-Associated Acid Phosphatase Activity Induced by Phosphate Starvation.
    Plant Physiol., 2016. 171(4): p. 2841-53
    [PMID:27329222]
  21. Song L, et al.
    The Molecular Mechanism of Ethylene-Mediated Root Hair Development Induced by Phosphate Starvation.
    PLoS Genet., 2016. 12(7): p. e1006194
    [PMID:27427911]
  22. Jeong J, et al.
    Phytochrome and Ethylene Signaling Integration in Arabidopsis Occurs via the Transcriptional Regulation of Genes Co-targeted by PIFs and EIN3.
    Front Plant Sci, 2016. 7: p. 1055
    [PMID:27486469]
  23. Tsai KJ,Lin CY,Ting CY,Shih MC
    Ethylene-Regulated Glutamate Dehydrogenase Fine-Tunes Metabolism during Anoxia-Reoxygenation.
    Plant Physiol., 2016. 172(3): p. 1548-1562
    [PMID:27677986]
  24. Zhang F, et al.
    EIN2-dependent regulation of acetylation of histone H3K14 and non-canonical histone H3K23 in ethylene signalling.
    Nat Commun, 2016. 7: p. 13018
    [PMID:27694846]
  25. Liu G, et al.
    Local Transcriptional Control of YUCCA Regulates Auxin Promoted Root-Growth Inhibition in Response to Aluminium Stress in Arabidopsis.
    PLoS Genet., 2016. 12(10): p. e1006360
    [PMID:27716807]
  26. Shen X,Li Y,Pan Y,Zhong S
    Activation of HLS1 by Mechanical Stress via Ethylene-Stabilized EIN3 Is Crucial for Seedling Soil Emergence.
    Front Plant Sci, 2016. 7: p. 1571
    [PMID:27822221]
  27. Shi H, et al.
    The Red Light Receptor Phytochrome B Directly Enhances Substrate-E3 Ligase Interactions to Attenuate Ethylene Responses.
    Dev. Cell, 2016. 39(5): p. 597-610
    [PMID:27889482]
  28. Wawrzyńska A,Sirko A
    EIN3 interferes with the sulfur deficiency signaling in Arabidopsis thaliana through direct interaction with the SLIM1 transcription factor.
    Plant Sci., 2016. 253: p. 50-57
    [PMID:27968996]
  29. Zemlyanskaya EV,Levitsky VG,Oshchepkov DY,Grosse I,Mironova VV
    The Interplay of Chromatin Landscape and DNA-Binding Context Suggests Distinct Modes of EIN3 Regulation in Arabidopsis thaliana.
    Front Plant Sci, 2016. 7: p. 2044
    [PMID:28119721]
  30. He X,Jiang J,Wang CQ,Dehesh K
    ORA59 and EIN3 interaction couples jasmonate-ethylene synergistic action to antagonistic salicylic acid regulation of PDF expression.
    J Integr Plant Biol, 2017. 59(4): p. 275-287
    [PMID:28168848]
  31. Abozeid A, et al.
    Ethylene Improves Root System Development under Cadmium Stress by Modulating Superoxide Anion Concentration in Arabidopsis thaliana.
    Front Plant Sci, 2017. 8: p. 253
    [PMID:28286514]
  32. Quan R, et al.
    EIN3 and SOS2 synergistically modulate plant salt tolerance.
    Sci Rep, 2017. 7: p. 44637
    [PMID:28300216]
  33. Kim GD,Cho YH,Yoo SD
    Regulatory Functions of Cellular Energy Sensor SNF1-Related Kinase1 for Leaf Senescence Delay through ETHYLENE- INSENSITIVE3 Repression.
    Sci Rep, 2017. 7(1): p. 3193
    [PMID:28600557]
  34. Liu Y, et al.
    Light and Ethylene Coordinately Regulate the Phosphate Starvation Response through Transcriptional Regulation of PHOSPHATE STARVATION RESPONSE1.
    Plant Cell, 2017. 29(9): p. 2269-2284
    [PMID:28842534]
  35. Liu X,Li Y,Zhong S
    Interplay between Light and Plant Hormones in the Control of Arabidopsis Seedling Chlorophyll Biosynthesis.
    Front Plant Sci, 2017. 8: p. 1433
    [PMID:28861105]
  36. Zhang F, et al.
    EIN2 mediates direct regulation of histone acetylation in the ethylene response.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(38): p. 10274-10279
    [PMID:28874528]
  37. Yan Z, et al.
    Type B Response Regulators Act As Central Integrators in Transcriptional Control of the Auxin Biosynthesis Enzyme TAA1.
    Plant Physiol., 2017. 175(3): p. 1438-1454
    [PMID:28931628]
  38. Liu X, et al.
    EIN3 and PIF3 Form an Interdependent Module That Represses Chloroplast Development in Buried Seedlings.
    Plant Cell, 2017. 29(12): p. 3051-3067
    [PMID:29114016]
  39. Feng Y, et al.
    Ethylene promotes root hair growth through coordinated EIN3/EIL1 and RHD6/RSL1 activity in Arabidopsis.
    Proc. Natl. Acad. Sci. U.S.A., 2017. 114(52): p. 13834-13839
    [PMID:29233944]
  40. Harkey AF, et al.
    Identification of Transcriptional and Receptor Networks That Control Root Responses to Ethylene.
    Plant Physiol., 2018. 176(3): p. 2095-2118
    [PMID:29259106]
  41. Zhang F,Wang L,Ko EE,Shao K,Qiao H
    Histone Deacetylases SRT1 and SRT2 Interact with ENAP1 to Mediate Ethylene-Induced Transcriptional Repression.
    Plant Cell, 2018. 30(1): p. 153-166
    [PMID:29298835]
  42. Lv B, et al.
    Brassinosteroids regulate root growth by controlling reactive oxygen species homeostasis and dual effect on ethylene synthesis in Arabidopsis.
    PLoS Genet., 2018. 14(1): p. e1007144
    [PMID:29324765]
  43. Dou L,He K,Higaki T,Wang X,Mao T
    Ethylene Signaling Modulates Cortical Microtubule Reassembly in Response to Salt Stress.
    Plant Physiol., 2018. 176(3): p. 2071-2081
    [PMID:29431630]
  44. Meng LS,Xu MK,Wan W,Wang JY
    Integration of Environmental and Developmental (or Metabolic) Control of Seed Mass by Sugar and Ethylene Metabolisms in Arabidopsis.
    J. Agric. Food Chem., 2018. 66(13): p. 3477-3488
    [PMID:29528636]
  45. Munné-Bosch S,Simancas B,Müller M
    Ethylene signaling cross-talk with other hormones in Arabidopsis thaliana exposed to contrasting phosphate availability: Differential effects in roots, leaves and fruits.
    J. Plant Physiol., 2018. 226: p. 114-122
    [PMID:29758376]